IMPACT OF LOW-LEVEL LASER THERAPY ON HAIR REGROWTH POST PRP TREATMENT

Abstract

Hair loss, especially androgenetic alopecia (AGA), significantly impacts individuals’ self-esteem and mental health. Low-Level Laser Therapy (LLLT) and Platelet-Rich Plasma (PRP) are non-invasive therapies gaining traction in hair restoration. While both therapies individually promote hair regrowth, the combined effects of LLLT post-PRP treatment remain underexplored Objective: This study aims to evaluate the impact of LLLT on hair regrowth following PRP treatment in patients with androgenetic alopecia, focusing on hair density, count, diameter, and anagen percentage. Methodology: A case-control study was conducted at Reshape Clinic Lahore with 22 androgenetic alopecia patients. The patients were randomized into two groups: Group A was administered LLLT after PRP treatment, and Group B was only given PRP treatment. Hair regrowth factors were assessed by Tricho Scan analysis and Physician's Global Assessment (PGA) scale at baseline, 6 weeks, and 12 weeks. Results: There was an enhancement in regrowth of hair for both groups, but Laser + PRP significantly manifested greater hair number, hair density, and anagen percentage. Statistical analysis revealed that Laser + PRP had larger effect, particularly by the 12th week (p = 0.001). The combined treatment was significantly superior compared with PRP in reducing telogen percentage. Conclusion: LLLT and PRP treatment offer superior outcome measures for hair regrowth compared with PRP monotherapy. The dual advantages between the two treatment regimens increase hair follicle regrowth and offer possible relief for the treatment of androgenetic alopecia. We advocate future research with larger sample sizes and longer follow-up periods to substantiate these findings.